Involvement of Aquaporin 3 in Helicobacter pylori-Related Gastric Diseases

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Involvement of Aquaporin 3 in Helicobacter pylori-Related Gastric Diseases

BACKGROUND Gastric cancer is one of the most common and lethal malignant cancers worldwide, and numerous epidemiological studies have demonstrated that Helicobacter pylori (H. pylori) infection plays a key role in the development of gastric carcinomas. Our previous studies showed that aquaporin 3 (AQP3) is overexpressed in gastric carcinoma and promotes the migration and proliferation of human ...

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Introduction: In addition to Helicobacter pylori, non-Helicobacter pylori helicobacters (NHPHs) have been diagnosed in the humans stomach that caused gastrointestinal diseases. This study aimed to evaluate the coinfection of H. pylori with NHPHs species in patients with gastric disorders in Iran.   Materials & Methods: This cross-sectional study was performed on 421 gastric biopsies form dysp...

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Helicobacter pylori ( H. pylori ) is associated with a wide spectrum of gastroduodenal diseases. Strong evidence has shown that H. pylori is implicated in the development of gastritis, gastric and duodenal ulcers, MALT lymphoma and gastric cancer. The result of multiple clinical trials had also found out that eradication of H. pylori results in cure of gastric and duodenal ulcers. The improveme...

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ژورنال

عنوان ژورنال: PLoS ONE

سال: 2012

ISSN: 1932-6203

DOI: 10.1371/journal.pone.0049104